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Drug: Lithium

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Total 11630 results found since Jan 2013.

Renal safety of lithium in HIV-infected patients established on tenofovir disoproxil fumarate containing antiretroviral therapy: analysis from a randomized placebo-controlled trial.
CONCLUSIONS: We found that 24-week treatment of HIV-infected patients with lithium and TDF did not result in increased nephrotoxicity. Trial registration The study was registered on the Pan African Clinical Trials Registry (PACTR) with the identifier number PACTR201310000635418. Registered 11 October 2013 before the first participant was enrolled. PMID: 28160772 [PubMed - in process]
Source: AIDS Research and Therapy - February 3, 2017 Category: Infectious Diseases Authors: Decloedt EH, Lesosky M, Maartens G, Joska JA Tags: AIDS Res Ther Source Type: research

A search map for organic additives and solvents applicable in high-voltage rechargeable batteries
Phys. Chem. Chem. Phys., 2016, Advance Article DOI: 10.1039/C6CP05800K, PaperMin Sik Park, Insun Park, Yoon-Sok Kang, Dongmin Im, Seok-Gwang Doo A search map composed of the redox potentials of [similar]1 000 000 organic compounds is theoretically generated for finding novel electrolytes. The quantitative relationship between the redox potentials and functional groups is suggested. The cycle performance of lithium ion batteries is improved by applying a screened anodic additive. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - September 19, 2016 Category: Chemistry Authors: Min Sik Park Source Type: research

Moderate to severe HIV-associated neurocognitive impairment: A randomized placebo-controlled trial of lithium
Conclusion: Adjunctive lithium pharmacotherapy in patients on ART with HAND was well tolerated but had no additional benefit on neurocognitive impairment.
Source: Medicine - November 1, 2016 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research

Fast material search of lithium ion conducting oxides using a recommender system
J. Mater. Chem. A, 2020, Advance Article DOI: 10.1039/D0TA02556A, PaperKota Suzuki, Kosei Ohura, Atsuto Seko, Yudai Iwamizu, Guowei Zhao, Masaaki Hirayama, Isao Tanaka, Ryoji Kanno Fast material search using a recommender system is demonstrated to obtain novel lithium ion conducting oxides. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - J. Mater. Chem. latest articles - June 5, 2020 Category: Chemistry Authors: Kota Suzuki Source Type: research

Sensors, Vol. 23, Pages 5465: Li2100deplMoO4 Scintillating Bolometers for Rare-Event Search Experiments
We report on the development of scintillating bolometers based on lithium molybdate crystals that contain molybdenum that has depleted into the double-β active isotope 100Mo (Li2100deplMoO4). We used two Li2100deplMoO4 cubic samples, each of which consisted of 45-millimeter sides and had a mass of 0.28 kg; these samples were produced following the purification and crystallization protocols developed for double-β search experiments with 100Mo-enriched Li2MoO4 crystals. Bolometric Ge detectors were utilized to register the scintillation photons that were emitted by the Li2100deplMoO4 crystal scintil...
Source: Sensors - June 9, 2023 Category: Biotechnology Authors: Iulian C. Bandac Alexander S. Barabash Laurent Berg é Yury A. Borovlev Jos é Maria Calvo-Mozota Paolo Carniti Maurice Chapellier Ioan Dafinei Fedor A. Danevich Louis Dumoulin Federico Ferri Andrea Giuliani Claudio Gotti Philippe Gras Veronika D. Grigori Tags: Article Source Type: research

Renal safety of lithium in HIV-infected patients established on tenofovir disoproxil fumarate containing antiretroviral therapy: analysis from a randomized placebo-controlled trial
The prevalence of bipolar disorder in HIV-infected patients is higher than the general population. Lithium is the most effective mood stabiliser, while tenofovir disoproxil fumarate (TDF) is frequently used as...
Source: AIDS Research and Therapy - February 4, 2017 Category: Infectious Diseases Authors: Eric H. Decloedt, Maia Lesosky, Gary Maartens and John A. Joska Source Type: research

Blood and cerebrospinal fluid biomarker changes in patients with HIV-associated neurocognitive impairment treated with lithium: analysis from a randomised placebo-controlled trial
AbstractHIV-associated neurocognitive disorders (HAND) persist in the era of antiretroviral therapy (ART). Thus, ART does not completely halt or reverse the pathological processes behind HAND. Adjuvant mitigating treatments are, therefore, prudent. Lithium treatment is known to promote neuronal brain –derived neurotrophic factors (BDNF). Lithium is also an inhibitor of glycogen synthase kinase-3 beta (GSK-3-β). We analyzed biomarkers obtained from participants in a randomized placebo-controlled trial of lithium in ART-treated individuals with moderate or severe HAND. We assayed markers at bas eline and 24 weeks across ...
Source: Journal of NeuroVirology - February 15, 2023 Category: Neurology Source Type: research

Search for common targets of lithium and valproic acid identifies novel epigenetic effects of lithium on the rat leptin receptor gene
ran & J B Potash
Source: Translational Psychiatry - July 14, 2015 Category: Psychiatry Authors: R S LeeM PiroozniaJ GuintivanoM LyE R EwaldK L TamashiroT D GouldT H MoranJ B Potash Source Type: research

Tamoxifen May Reduce Mania in Patients With Bipolar Disorder But Questions Remain
Tamoxifen, a medication commonly used to treat breast cancer, appears to hold some promise as a treatment for mania, according to asystematic review and meta-analysisappearing in theJournal of Psychopharmacology.Tamoxifen has been proposed as a treatment for bipolar disorder because it acts on cells in a way similar to lithium and valproate —both of which are effective medications for bipolar disorder. However, the current review found most studies focused on the effect of tamoxifen on mania, not on bipolar disorder, and its effects on depression are unknown.“Tamoxifen appears to be a promising potential treatment for ...
Source: Psychiatr News - February 15, 2019 Category: Psychiatry Tags: bipolar disorder depression Journal of Psychopharmacology literature search mania meta-analysis systematic review tamoxifen Source Type: research

The binary boron lithium clusters B12Lin with n = 1 – 14: In search for hydrogen storage materials
Phys. Chem. Chem. Phys., 2021, Accepted Manuscript DOI: 10.1039/D1CP03682C, PaperLong Van Duong, Nguyen Thanh Si, Nguyen Phi Hung, Minh T. Nguyen (Abstract) Molecular structures and properties of the binary clusters containing twelve boron atoms mixed with n lithium atoms, B12Lin with n = 1 – 14, were investigated using density functional... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - October 25, 2021 Category: Chemistry Authors: Long Van Duong Source Type: research

The binary boron lithium clusters B12Lin with n = 1 –14: in search for hydrogen storage materials
Phys. Chem. Chem. Phys., 2021, Advance Article DOI: 10.1039/D1CP03682C, PaperLong Van Duong, Nguyen Thanh Si, Nguyen Phi Hung, Minh Tho Nguyen Molecular structures and properties of the binary clusters containing twelve boron atoms mixed withn lithium atoms, B12Lin withn = 1 –14, were investigated using density functional theory with the TPSSh functional and the 6-311+G(d) basis set. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - November 1, 2021 Category: Chemistry Authors: Long Van Duong Source Type: research

Topical antifungals for seborrhoeic dermatitis.
CONCLUSIONS: Ketoconazole and ciclopirox are more effective than placebo, but limited evidence suggests that either of these agents is more effective than any other agent within the same class. Very few studies have assessed symptom clearance for longer periods than four weeks. Ketoconazole produced findings similar to those of steroids, but side effects were fewer. Treatment effect on overall quality of life remains unknown. Better outcome measures, studies of better quality and better reporting are all needed to improve the evidence base for antifungals for seborrhoeic dermatitis. PMID: 25919043 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - April 28, 2015 Category: Journals (General) Authors: Okokon EO, Verbeek JH, Ruotsalainen JH, Ojo OA Tags: Cochrane Database Syst Rev Source Type: research

The efficacy of new 2,5-dihydroxybenzyl derivatives against Trypanosoma cruzi, Leishmania infantum and Leishmania braziliensis
Conclusion: This evidence suggests that the anti-parasitic activity observed in these analogs is affected by the size of the group at the 4-position of the second ring, but not related with electronic factors.This study identified hit compounds with the potential to target several kinetoplastid parasites.
Source: The Journal of Infection in Developing Countries - June 30, 2019 Category: Infectious Diseases Source Type: research

Brain Citrullination Patterns and T Cell Reactivity of Cerebrospinal Fluid-Derived CD4+ T Cells in Multiple Sclerosis
We report many of them for the first time. For the already described citrullinated proteins MBP, GFAP, and vimentin, we could identify additional citrullinated sites. The number of modified proteins in MS white matter was higher than control tissue. Citrullinated peptides are considered neoepitopes that may trigger autoreactivity. We used newly identified epitopes and previously reported immunodominant myelin peptides in their citrullinated and non-citrullinated form to address the recognition of CSF-infiltrating CD4+ T cells from 22 MS patients by measuring proliferation and IFN-γ secretion. We did not detect ...
Source: Frontiers in Immunology - April 9, 2019 Category: Allergy & Immunology Source Type: research